Interest of a dermo-cosmetic product in the management of radiodermatitis in breast cancer

The quantity of total lipids increased significantly by +21%, and the TEWL decreased significantly by -11.8% after 4 weeks of product application. In the clinical study, erythema (-90%), dryness (-100%), and desquamation (-100%) decreased significantly and the lesions disappeared in 93.3% of the subjects. The product was deemed good to very good as a supportive care in radiotherapy by the investigators. The intensity of burning sensation decreased significantly by -73.5%, and pain or itching were not relevant. 82.2% to 93.3% of the subjects agreed that the product nourishes and restores the skin, reduces discomfort and protects the skin from radiotherapy. The product was very well tolerated by all subjects and no negative effect was observed on subject’s quality of life.

Topical application of a specific dermo-cosmetic product, with an appropriate protocol, maintain skin hydration and integrity, making this exhausting process less traumatic to patients, and easier to complete.

Helena Polena¹, Arnaud Fontbonne^1,2, Nathalie Ardiet¹, Marlène Chavagnac-Bonneville^1,2, Christelle Graizeau, Sandra Trompezinski^1,2 and Michèle Sayag¹

¹NAOS Group, Research and Development Department, Lyon, France

²NAOS Institute of Life Science, Aix-en-Provence, France

Polena H.¹, Fontbonne A.^1,2, Ardiet N.¹, Chavagnac-Bonneville M.^1,2, Trompezinski S^1,2, and Sayag M.¹

¹NAOS Group, Research and Development Department, Aix-en-Provence, France

²NAOS Institute of Life Science, Aix-en-Provence, France